Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development

INTRODUCTION: Collagen-induced arthritis (CIA) is a mouse model for rheumatoid arthritis (RA) and is induced after immunization with type II collagen (CII). CIA, like RA, is an autoimmune disease leading to destruction of cartilage and joints, and both the priming and inflammatory phases have been s...

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Hauptverfasser: Bäcklund, Alexandra, Holmdahl, Meirav, Mattsson, Ragnar, Håkansson, Katarina, Lindström, Veronica, Nandakumar, Kutty Selva, Grubb, Anders, Holmdahl, Rikard
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132044/
https://ncbi.nlm.nih.gov/pubmed/21443774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3298
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