Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development

INTRODUCTION: Collagen-induced arthritis (CIA) is a mouse model for rheumatoid arthritis (RA) and is induced after immunization with type II collagen (CII). CIA, like RA, is an autoimmune disease leading to destruction of cartilage and joints, and both the priming and inflammatory phases have been s...

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Main Authors: Bäcklund, Alexandra, Holmdahl, Meirav, Mattsson, Ragnar, Håkansson, Katarina, Lindström, Veronica, Nandakumar, Kutty Selva, Grubb, Anders, Holmdahl, Rikard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132044/
https://ncbi.nlm.nih.gov/pubmed/21443774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3298
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