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Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells

Antibodies against type II collagen (anti-CII) are arthritogenic and have a crucial role in the initiation of collagen-induced arthritis. Here, we have determined the dependence of T and B cells in collagen-antibody-induced arthritis (CAIA) during different phases of arthritis. Mice deficient for B...

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Main Authors: Nandakumar, Kutty Selva, Bäcklund, Johan, Vestberg, Mikael, Holmdahl, Rikard
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064861/
https://ncbi.nlm.nih.gov/pubmed/15535832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1217
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