Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice

INTRODUCTION: Antibodies towards type II collagen (CII) are detected in patients with rheumatoid arthritis (RA) and in non-human primates and rodents with collagen induced arthritis (CIA). We have previously shown that antibodies specific for several CII-epitopes are pathogenic using monoclonal anti...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Lindh, Ingrid, Snir, Omri, Lönnblom, Erik, Uysal, Hüseyin, Andersson, Ida, Nandakumar, Kutty Selva, Vierboom, Michel, 't Hart, Bert, Malmström, Vivianne, Holmdahl, Rikard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226996/
https://ncbi.nlm.nih.gov/pubmed/25005029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4605
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