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Kinetics and thermodynamics of amyloid formation from direct measurements of fluctuations in fibril mass

Aggregation of proteins and peptides is a widespread and much-studied problem, with serious implications in contexts ranging from biotechnology to human disease. An understanding of the proliferation of such aggregates under specific conditions requires a quantitative knowledge of the kinetics and t...

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Detalhes bibliográficos
Main Authors: Knowles, Tuomas P. J., Shu, Wenmiao, Devlin, Glyn L., Meehan, Sarah, Auer, Stefan, Dobson, Christopher M., Welland, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891240/
https://ncbi.nlm.nih.gov/pubmed/17540728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610659104
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