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Characterization of the nanoscale properties of individual amyloid fibrils

We report the detailed mechanical characterization of individual amyloid fibrils by atomic force microscopy and spectroscopy. These self-assembling materials, formed here from the protein insulin, were shown to have a strength of 0.6 ± 0.4 GPa, comparable to that of steel (0.6–1.8 GPa), and a mechan...

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Bibliografiset tiedot
Päätekijät: Smith, Jeffrey F., Knowles, Tuomas P. J., Dobson, Christopher M., MacPhee, Cait E., Welland, Mark E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635084/
https://ncbi.nlm.nih.gov/pubmed/17038504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604035103
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