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The formation of spherulites by amyloid fibrils of bovine insulin
Bovine insulin has long been known to self-assemble in vitro into amyloid fibrils. We have observed a further higher-order self-association of the protein into spherical structures, with diameters typically around 50 μm but ranging from 10 to 150 μm. In a polarizing light microscope, these structure...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521966/ https://ncbi.nlm.nih.gov/pubmed/15381766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405933101 |
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