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The formation of spherulites by amyloid fibrils of bovine insulin

Bovine insulin has long been known to self-assemble in vitro into amyloid fibrils. We have observed a further higher-order self-association of the protein into spherical structures, with diameters typically around 50 μm but ranging from 10 to 150 μm. In a polarizing light microscope, these structure...

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Bibliografski detalji
Glavni autori: Krebs, Mark R. H., MacPhee, Cait E., Miller, Aline F., Dunlop, Iain E., Dobson, Christopher M., Donald, Athene M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC521966/
https://ncbi.nlm.nih.gov/pubmed/15381766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405933101
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