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High-resolution molecular structure of a peptide in an amyloid fibril determined by magic angle spinning NMR spectroscopy

Amyloid fibrils are self-assembled filamentous structures associated with protein deposition conditions including Alzheimer's disease and the transmissible spongiform encephalopathies. Despite the immense medical importance of amyloid fibrils, no atomic-resolution structures are available for t...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Jaroniec, Christopher P., MacPhee, Cait E., Bajaj, Vikram S., McMahon, Michael T., Dobson, Christopher M., Griffin, Robert G.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321745/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14715898/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0304849101
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