High-resolution molecular structure of a peptide in an amyloid fibril determined by magic angle spinning NMR spectroscopy

Amyloid fibrils are self-assembled filamentous structures associated with protein deposition conditions including Alzheimer's disease and the transmissible spongiform encephalopathies. Despite the immense medical importance of amyloid fibrils, no atomic-resolution structures are available for these...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Jaroniec, Christopher P., MacPhee, Cait E., Bajaj, Vikram S., McMahon, Michael T., Dobson, Christopher M., Griffin, Robert G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2004
Soggetti:	Physical Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14715898/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0304849101
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