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BRCA2 is required for neurogenesis and suppression of medulloblastoma

Defective DNA damage responses in the nervous system can result in neurodegeneration or tumorigenesis. Despite the importance of DNA damage signalling, the neural function of many critical DNA repair factors is unclear. BRCA2 is necessary for homologous recombination repair of DNA and the prevention...

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Autors principals: Frappart, Pierre-Olivier, Lee, Youngsoo, Lamont, Jayne, McKinnon, Peter J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888666/
https://ncbi.nlm.nih.gov/pubmed/17476307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601703
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