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BRCA2 is required for neurogenesis and suppression of medulloblastoma
Defective DNA damage responses in the nervous system can result in neurodegeneration or tumorigenesis. Despite the importance of DNA damage signalling, the neural function of many critical DNA repair factors is unclear. BRCA2 is necessary for homologous recombination repair of DNA and the prevention...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1888666/ https://ncbi.nlm.nih.gov/pubmed/17476307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601703 |
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