Načítá se...

Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors

The rapid proliferation of progenitors during neurogenesis requires a stringent genomic maintenance program to ensure transmission of genetic fidelity. However the essential factors that govern neural progenitor genome integrity are unknown. Here we report that conditional inactivation of mouse TopB...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Lee, Youngsoo, Katyal, Sachin, Downing, Susanna M., Zhao, Jingfeng, Russell, Helen R., McKinnon, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404252/
https://ncbi.nlm.nih.gov/pubmed/22522401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3097
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!