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Treslin Collaborates with TopBP1 in Triggering the Initiation of DNA Replication

TopBP1 has important roles in both DNA replication and checkpoint regulation in vertebrates. We have identified a protein called Treslin that associates with TopBP1 in Xenopus egg extracts. Depletion of Treslin from egg extracts strongly inhibits chromosomal DNA replication. Binding of Treslin to ch...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kumagai, Akiko, Shevchenko, Anna, Shevchenko, Andrej, Dunphy, William G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857569/
https://ncbi.nlm.nih.gov/pubmed/20116089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.12.049
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