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Treslin Collaborates with TopBP1 in Triggering the Initiation of DNA Replication
TopBP1 has important roles in both DNA replication and checkpoint regulation in vertebrates. We have identified a protein called Treslin that associates with TopBP1 in Xenopus egg extracts. Depletion of Treslin from egg extracts strongly inhibits chromosomal DNA replication. Binding of Treslin to ch...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857569/ https://ncbi.nlm.nih.gov/pubmed/20116089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.12.049 |
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