Interaction of Chk1 with Treslin Negatively Regulates the Initiation of Chromosomal DNA Replication

Treslin helps to trigger the initiation of DNA replication by promoting integration of Cdc45 into the replicative helicase. Treslin is a key positive-regulatory target of cell cycle control mechanisms; activation of Treslin by cyclin-dependent kinase is essential for the initiation of replication. H...

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Foilsithe in:Mol Cell
Main Authors: Guo, Cai, Kumagai, Akiko, Schlacher, Katharina, Shevchenko, Anna, Shevchenko, Andrej, Dunphy, William G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321788/
https://ncbi.nlm.nih.gov/pubmed/25557548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.12.003
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