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MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication
Treslin, which is essential for incorporation of Cdc45 into the replicative helicase, possesses a partner called MTBP (Mdm2-binding protein). We have analyzed Xenopus and human MTBP to assess its role in DNA replication. Depletion of MTBP from Xenopus egg extracts, which also removes Treslin, abolis...
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| Опубликовано в: : | Mol Biol Cell |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Cell Biology
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5662258/ https://ncbi.nlm.nih.gov/pubmed/28877985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-07-0448 |
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