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MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication

Treslin, which is essential for incorporation of Cdc45 into the replicative helicase, possesses a partner called MTBP (Mdm2-binding protein). We have analyzed Xenopus and human MTBP to assess its role in DNA replication. Depletion of MTBP from Xenopus egg extracts, which also removes Treslin, abolis...

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Библиографические подробности
Опубликовано в: :Mol Biol Cell
Главные авторы: Kumagai, Akiko, Dunphy, William G.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662258/
https://ncbi.nlm.nih.gov/pubmed/28877985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-07-0448
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