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Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication

The processes that control where higher eukaryotic cells initiate DNA replication throughout the genome are not understood clearly. In metazoans, the Treslin-MTBP complex mediates critical final steps in formation of the activated replicative helicase prior to initiation of replication. Here, we map...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Kumagai, Akiko, Dunphy, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523632/
https://ncbi.nlm.nih.gov/pubmed/32966791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108178
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