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Topologies of a Substrate Protein Bound to the Chaperonin GroEL
The chaperonin GroEL assists polypeptide folding through sequential steps of binding nonnative protein in the central cavity of an open ring, via hydrophobic surfaces of its apical domains, followed by encapsulation in a hydrophilic cavity. To examine the binding state, we have classified a large da...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cell Press
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885994/ https://ncbi.nlm.nih.gov/pubmed/17499047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.04.004 |
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