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Substrate polypeptide presents a load on the apical domains of the chaperonin GroEL

A conundrum has arisen in the study of the structural states of the GroEL–GroES chaperonin machine: When either ATP or ADP is added along with GroES to GroEL, the same asymmetric complex, with one ring in a GroES-domed state, is observed by either x-ray crystallographic study or cryoelectron microsc...

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Autors principals: Motojima, Fumihiro, Chaudhry, Charu, Fenton, Wayne A., Farr, George W., Horwich, Arthur L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC523455/
https://ncbi.nlm.nih.gov/pubmed/15479763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406132101
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