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Allosteric signalling of ATP hydrolysis in GroEL-GroES complexes

The double ring chaperonin GroEL and its lid-like co-chaperonin GroES form asymmetric complexes that in the ATP-bound state mediate productive folding in a hydrophilic, GroES-encapsulated chamber, the so-called cis cavity. Upon ATP hydrolysis within the cis ring, the asymmetric complex becomes able...

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Detalhes bibliográficos
Main Authors: Ranson, Neil A., Clare, Daniel K., Farr, George W., Houldershaw, David, Horwich, Arthur L., Saibil, Helen R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871290/
https://ncbi.nlm.nih.gov/pubmed/16429154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1046
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