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Folding with and without encapsulation by cis- and trans-only GroEL–GroES complexes

Although a cis mechanism of GroEL-mediated protein folding, occurring inside a hydrophilic chamber encapsulated by the co-chaperonin GroES, has been well documented, recently the GroEL–GroES-mediated folding of aconitase, a large protein (82 kDa) that could not be encapsulated, was described. This p...

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Detalhes bibliográficos
Main Authors: Farr, George W., Fenton, Wayne A., Chaudhuri, Tapan K., Clare, Daniel K., Saibil, Helen R., Horwich, Arthur L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165638/
https://ncbi.nlm.nih.gov/pubmed/12839985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg313
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