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Folding with and without encapsulation by cis- and trans-only GroEL–GroES complexes

Although a cis mechanism of GroEL-mediated protein folding, occurring inside a hydrophilic chamber encapsulated by the co-chaperonin GroES, has been well documented, recently the GroEL–GroES-mediated folding of aconitase, a large protein (82 kDa) that could not be encapsulated, was described. This p...

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Vydáno v:EMBO J
Hlavní autoři: Farr, George W., Fenton, Wayne A., Chaudhuri, Tapan K., Clare, Daniel K., Saibil, Helen R., Horwich, Arthur L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165638/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12839985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg313
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