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Role of the γ-phosphate of ATP in triggering protein folding by GroEL–GroES: function, structure and energetics
Productive cis folding by the chaperonin GroEL is triggered by the binding of ATP but not ADP, along with cochaperonin GroES, to the same ring as non-native polypeptide, ejecting polypeptide into an encapsulated hydrophilic chamber. We examined the specific contribution of the γ-phosphate of ATP to...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC204461/ https://ncbi.nlm.nih.gov/pubmed/14517228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg477 |
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