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Direct NMR observation of a substrate protein bound to the chaperonin GroEL

The reaction cycle and the major structural states of the molecular chaperone GroEL and its cochaperone, GroES, are well characterized. In contrast, very little is known about the nonnative states of the substrate polypeptide acted on by the chaperonin machinery. In this study, we investigated the s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Horst, Reto, Bertelsen, Eric B., Fiaux, Jocelyne, Wider, Gerhard, Horwich, Arthur L., Wüthrich, Kurt
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1188259/
https://ncbi.nlm.nih.gov/pubmed/16116078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505642102
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