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TRANSGENIC OVEREXPRESSION OF RASGRP1 IN MOUSE EPIDERMIS RESULTS IN SPONTANEOUS TUMORS OF THE SKIN
RasGRP1 is a guanine nucleotide exchange factor for Ras and a receptor of the second messenger diacylglycerol and its ultrapotent analogs, the phorbol esters. We have recently shown expression of RasGRP1 in the epidermal keratinocytes, where it can mediate Ras activation in response to the phorbol e...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885541/ https://ncbi.nlm.nih.gov/pubmed/17210708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-3080 |
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