Overexpression of TC-PTP in murine epidermis attenuates skin tumor formation

T-cell protein tyrosine phosphatase (TC-PTP), encoded by Ptpn2, has been shown to function as a tumor suppressor during skin carcinogenesis. In the current study, we generated a novel epidermal specific TC-PTP-overexpressing (K5HA.Ptpn2) mouse model to show that TC-PTP contributes to the attenuation...

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Udgivet i:Oncogene
Main Authors: Kim, Mihwa, Morales, Liza D., Lee, Cheol Jung, Olivarez, Serena A., Kim, Woo Jin, Hernandez, Joselin, Mummidi, Srinivas, Jenkinson, Christopher, Tsin, Andrew T., Jang, Ik-Soon, Slaga, Thomas J., Kim, Dae Joon
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244373/
https://ncbi.nlm.nih.gov/pubmed/32286519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1282-8
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