UVB-induced nuclear translocation of TC-PTP by AKT/14-3-3σ axis inhibits keratinocyte survival and proliferation

Understanding protein subcellular localization is important to determining the functional role of specific proteins. T-cell protein tyrosine phosphatase (TC-PTP) contains bipartite nuclear localization signals (NLSI and NLSII) in its C-terminus. We previously have demonstrated that the nuclear form...

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Vydáno v:Oncotarget
Hlavní autoři: Kim, Mihwa, Morales, Liza D., Baek, Minwoo, Slaga, Thomas J., DiGiovanni, John, Kim, Dae Joon
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
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Priority Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710877/
https://ncbi.nlm.nih.gov/pubmed/29207596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21794
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