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Differential effects of bryostatin 1 and 12-O-tetradecanoyl-phorbol-13-acetate on the regulation and activation of RasGRP1 in mouse epidermal keratinocytes
The antitumor agent Bryostatin 1 (Bryo) and the tumor promoting phorbol esters function as structural mimetics of the second lipid messenger diacylglycerol (DAG) by binding to the C1 domain of DAG receptors. However, Bryo and the phorbol esters often differ in their cellular actions. In mouse skin,...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885540/ https://ncbi.nlm.nih.gov/pubmed/16546974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-05-0317 |
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