Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer

AIMS: The aim of this exploratory study was to investigate associations between irinotecan pharmacokinetic parameters and allelic variants in genes encoding for drug transporters and drug metabolizing enzymes that are involved in irinotecan disposition in Asian patients with cancer. METHODS: Irinote...

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Hlavní autoři: Zhou, Qingyu, Sparreboom, Alex, Tan, Eng-Huat, Cheung, Yin-Bun, Lee, Ann, Poon, Donald, Lee, Edmund J D, Chowbay, Balram
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2005
Témata:
Pharmacogenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884809/
https://ncbi.nlm.nih.gov/pubmed/15801936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02330.x
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