Association of CYP2C19*2 and associated haplotypes with lower norendoxifen concentrations in tamoxifen‐treated Asian breast cancer patients

AIM: The aim was to examine the influence of CYP2C19 variants and associated haplotypes on the disposition of tamoxifen and its metabolites, particularly norendoxifen (NorEND), in Asian patients with breast cancer. METHODS: Sixty‐six CYP2C19 polymorphisms were identified in healthy Asians (n = 240),...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Lim, Joanne Siok Liu, Sutiman, Natalia, Muerdter, Thomas E., Singh, Onkar, Cheung, Yin Bun, Ng, Raymond Chee Hui, Yap, Yoon Sim, Wong, Nan Soon, Ang, Peter Cher Siang, Dent, Rebecca, Schroth, Werner, Schwab, Matthias, Chowbay, Balram
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Pharmacogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876188/
https://ncbi.nlm.nih.gov/pubmed/26799162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12886
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados