Meta-analysis of the influence of MDR1 C3435T polymorphism on digoxin pharmacokinetics and MDR1 gene expression

AIMS: Studies revealing conflicting results of the functional significance of MDR1 exon 26 C3435T SNP on the disposition of digoxin in different ethnic groups led us to perform a meta-analysis on published data investigating the influence of C3435T SNP on the pharmacokinetics of digoxin and the expr...

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Bibliographic Details
Main Authors: Chowbay, Balram, Li, Huihua, David, Machin, Bun Cheung, Yin, Lee, Edmund J D
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2005
Subjects:
Pharmacogenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884933/
https://ncbi.nlm.nih.gov/pubmed/16042669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02392.x
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