Influence of the CYP3A5 and MDR1 genetic polymorphisms on the pharmacokinetics of tacrolimus in healthy Korean subjects

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: It was found that the genetic polymorphisms of CYP3A5, CYP3A4 and MDR1 could affect the pharmacokinetics of tacrolimus. This study was conducted to find such a possibility in the Korean population. WHAT THIS STUDY ADDS: CYP3A5 polymorphisms are likely to be...

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Bibliografiske detaljer
Main Authors: Choi, Ji H, Lee, Yoon J, Jang, Seong B, Lee, Jong-Eun, Kim, Kyung H, Park, Kyungsoo
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2007
Fag:
Pharmacogenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1974827/
https://ncbi.nlm.nih.gov/pubmed/17391324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02874.x
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