Effects of cytochrome P450 oxidoreductase genotypes on the pharmacokinetics of amlodipine in healthy Korean subjects

BACKGROUND: The aim of this study was to investigate the effects of P450 oxidoreductase (POR) genetic polymorphisms on the pharmacokinetic parameters of amlodipine. METHODS: After a single 10‐mg dose of amlodipine administration, 25 healthy male subjects completed genotyping for 12 single nucleotide...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Han, Ji Min, Yee, Jeong, Chung, Jee Eun, Lee, Kyung Eun, Park, Kyungsoo, Gwak, Hye Sun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216797/
https://ncbi.nlm.nih.gov/pubmed/32134573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1201
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