Effect of ketoconazole on the pharmacokinetics of udenafil in healthy Korean subjects

AIMS: Udenafil is a phosphodiesterase 5 inhibitor used for the treatment of erectile dysfunction. It is metabolized to DA-8164, a major metabolite, by CYP3A4. This study was performed to investigate the effect of ketoconazole, a known CYP3A4 inhibitor, on the pharmacokinetics of udenafil. METHODS: A...

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Hlavní autoři: Shin, Kwang-Hee, Chung, Yong-ju, Kim, Bo-Hyung, Kim, Tae-Eun, Kim, Hwa-Sook, Cho, Joo-Youn, Jang, In-Jin, Shin, Sang-Goo, Yu, Kyung-Sang
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2010
Témata:
Short Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829702/
https://ncbi.nlm.nih.gov/pubmed/20233203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03601.x
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