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Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer

AIMS: The aim of this exploratory study was to investigate associations between irinotecan pharmacokinetic parameters and allelic variants in genes encoding for drug transporters and drug metabolizing enzymes that are involved in irinotecan disposition in Asian patients with cancer. METHODS: Irinote...

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Bibliografiske detaljer
Main Authors: Zhou, Qingyu, Sparreboom, Alex, Tan, Eng-Huat, Cheung, Yin-Bun, Lee, Ann, Poon, Donald, Lee, Edmund J D, Chowbay, Balram
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884809/
https://ncbi.nlm.nih.gov/pubmed/15801936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02330.x
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