Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer

AIMS: The aim of this exploratory study was to investigate associations between irinotecan pharmacokinetic parameters and allelic variants in genes encoding for drug transporters and drug metabolizing enzymes that are involved in irinotecan disposition in Asian patients with cancer. METHODS: Irinote...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Qingyu, Sparreboom, Alex, Tan, Eng-Huat, Cheung, Yin-Bun, Lee, Ann, Poon, Donald, Lee, Edmund J D, Chowbay, Balram
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2005
Schlagworte:
Pharmacogenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884809/
https://ncbi.nlm.nih.gov/pubmed/15801936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02330.x
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