Pharmacogenetic profiling across the irinotecan pathway in Asian patients with cancer

AIMS: The aim of this exploratory study was to investigate associations between irinotecan pharmacokinetic parameters and allelic variants in genes encoding for drug transporters and drug metabolizing enzymes that are involved in irinotecan disposition in Asian patients with cancer. METHODS: Irinote...

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Bibliografische gegevens
Hoofdauteurs: Zhou, Qingyu, Sparreboom, Alex, Tan, Eng-Huat, Cheung, Yin-Bun, Lee, Ann, Poon, Donald, Lee, Edmund J D, Chowbay, Balram
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2005
Onderwerpen:
Pharmacogenetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884809/
https://ncbi.nlm.nih.gov/pubmed/15801936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02330.x
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