Nootropic α7 nicotinic receptor allosteric modulator derived from GABA(A) receptor modulators

Activation of brain α7 nicotinic acetylcholine receptors (α7 nAChRs) has broad therapeutic potential in CNS diseases related to cognitive dysfunction, including Alzheimer's disease and schizophrenia. In contrast to direct agonist activation, positive allosteric modulation of α7 nAChRs would del...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ng, Herman J., Whittemore, Edward R., Tran, Minhtam B., Hogenkamp, Derk J., Broide, Ron S., Johnstone, Timothy B., Zheng, Lijun, Stevens, Karen E., Gee, Kelvin W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2007
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876571/
https://ncbi.nlm.nih.gov/pubmed/17470817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701321104
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