Limiting Activity at β(1)-Subunit-Containing GABA(A) Receptor Subtypes Reduces Ataxia

GABA(A) receptor (R) positive allosteric modulators that selectively modulate GABA(A)Rs containing β(2)- and/or β(3)- over β(1)-subunits have been reported across diverse chemotypes. Examples include loreclezole, mefenamic acid, tracazolate, and etifoxine. In general,“β(2/3)-selective” GABA(A)R posi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Gee, Kelvin W., Tran, Minhtam B., Hogenkamp, Derk J., Johnstone, Timothy B., Bagnera, Rudy E., Yoshimura, Ryan F., Huang, Jin-Cheng, Belluzzi, James D., Whittemore, Edward R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2010
Soggetti:
Neuropharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835428/
https://ncbi.nlm.nih.gov/pubmed/19940102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.161885
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi