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Inhibition of Human Telomerase Activity by an Engineered Zinc Finger Protein that Binds G-Quadruplexes
The G-quadruplex nucleic acid structural motif is a target for designing molecules that could potentially modulate telomere length or have anticancer properties. We have recently described an engineered zinc finger protein (Gq1) that binds with specificity to the intramolecular G-quadruplex formed b...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876260/ https://ncbi.nlm.nih.gov/pubmed/15491152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi048892t |
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