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Inhibition of Human Telomerase Activity by an Engineered Zinc Finger Protein that Binds G-Quadruplexes

The G-quadruplex nucleic acid structural motif is a target for designing molecules that could potentially modulate telomere length or have anticancer properties. We have recently described an engineered zinc finger protein (Gq1) that binds with specificity to the intramolecular G-quadruplex formed b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Patel, Sachin D., Isalan, Mark, Gavory, Gérald, Ladame, Sylvain, Choo, Yen, Balasubramanian, Shankar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876260/
https://ncbi.nlm.nih.gov/pubmed/15491152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi048892t
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