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Inhibition of Human Telomerase Activity by an Engineered Zinc Finger Protein that Binds G-Quadruplexes

The G-quadruplex nucleic acid structural motif is a target for designing molecules that could potentially modulate telomere length or have anticancer properties. We have recently described an engineered zinc finger protein (Gq1) that binds with specificity to the intramolecular G-quadruplex formed b...

詳細記述

保存先:
書誌詳細
主要な著者: Patel, Sachin D., Isalan, Mark, Gavory, Gérald, Ladame, Sylvain, Choo, Yen, Balasubramanian, Shankar
フォーマット: Artigo
言語:Inglês
出版事項: 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876260/
https://ncbi.nlm.nih.gov/pubmed/15491152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi048892t
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