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Inhibition of Human Telomerase Activity by an Engineered Zinc Finger Protein that Binds G-Quadruplexes

The G-quadruplex nucleic acid structural motif is a target for designing molecules that could potentially modulate telomere length or have anticancer properties. We have recently described an engineered zinc finger protein (Gq1) that binds with specificity to the intramolecular G-quadruplex formed b...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Patel, Sachin D., Isalan, Mark, Gavory, Gérald, Ladame, Sylvain, Choo, Yen, Balasubramanian, Shankar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876260/
https://ncbi.nlm.nih.gov/pubmed/15491152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi048892t
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