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Synthesis and G-quadruplex binding studies of new 4-N-methylpyridinium porphyrins

A series of cationic porphyrins carrying 1–3 meso-N-pyridinium groups has been synthesised, and their binding to G-quadruplex DNA has been explored by surface plasmon resonance (SPR) and circular dichroism spectroscopy. Two trans substituents appear to be sufficient for tight binding; preferential b...

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Bibliografiske detaljer
Main Authors: Gonçalves, Diana P. N., Ladame, Sylvain, Balasubramanian, Shankar, Sanders, Jeremy K. M.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195891/
https://ncbi.nlm.nih.gov/pubmed/17036123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b608494j
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