A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels

Plasma factor VIII coagulant activity (FVIII:C) level is a highly heritable quantitative trait that is strongly correlated with thrombosis risk. Polymorphisms within only 1 gene, the ABO blood-group locus, have been unequivocally demonstrated to contribute to the broad population variability observe...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Viel, Kevin R., Machiah, Deepa K., Warren, Diane M., Khachidze, Manana, Buil, Alfonso, Fernstrom, Karl, Souto, Juan C., Peralta, Juan M., Smith, Todd, Blangero, John, Porter, Sandra, Warren, Stephen T., Fontcuberta, Jordi, Soria, Jose M., Dana Flanders, W., Almasy, Laura, Howard, Tom E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2007
Θέματα:
Hemostasis, Thrombosis, and Vascular Biology
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874571/
https://ncbi.nlm.nih.gov/pubmed/17209060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-026104
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