Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study

Total plasma homocysteine concentration (tHcy) is a biomarker for atherothrombotic disease, but causality remains uncertain. Polymorphisms in the genes involved in methionine metabolism explain only a small fraction of the heritability of tHcy levels. In a genome-wide association study, we examined...

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Bibliografiska uppgifter
Huvudupphovsmän: Mälarstig, Anders, Buil, Alfonso, Souto, Juan Carolos, Clarke, Robert, Blanco-Vaca, Francisco, Fontcuberta, Jordi, Peden, John, Andersen, Malin, Silveira, Angela, Barlera, Simona, Seedorf, Udo, Watkins, Hugh, Almasy, Laura, Hamsten, Anders, Soria, José Manuel
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2009
Ämnen:
Thrombosis and Hemostasis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727417/
https://ncbi.nlm.nih.gov/pubmed/19525478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-04-215269
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