Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: Implications for Huntington's disease therapy

The accumulation of insoluble protein aggregates in intra and perinuclear inclusions is a hallmark of Huntington's disease (HD) and related glutamine-repeat disorders. A central question is whether protein aggregation plays a direct role in the pathogenesis of these neurodegenerative diseases....

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Heiser, Volker, Scherzinger, Eberhard, Boeddrich, Annett, Nordhoff, Eckhard, Lurz, Rudi, Schugardt, Nancy, Lehrach, Hans, Wanker, Erich E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2000
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC18723/
https://ncbi.nlm.nih.gov/pubmed/10829068
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller