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Huntington's disease: from gene to potential therapy

Huntington's disease (HD) is a progressive, late-onset neurodegenerative illness with autosomal dominant inheritance that affects one in 10 000 individuals in Western Europe. The disease is caused by a polyglutamine repeat expansion located in the N-terminal region of the huntingtin protein. Th...

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Détails bibliographiques
Auteurs principaux: Lehrach, Hans, Wanker, Erich E.
Format: Artigo
Langue:Inglês
Publié: Les Laboratoires Servier 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181644/
https://ncbi.nlm.nih.gov/pubmed/22034471
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