Gene Silencing Therapies for Huntington’s Disease
Huntington’s disease (HD) is a rare, autosomal‑dominant neurodegenerative disorder precipitated by a pathological expansion of CAG trinucleotide repeats in exon 1 of the huntingtin (HTT) gene. Mutant huntingtin (mHTT) imposes a toxic gain‑of‑function that progressively compromises neuronal circuitry...
שמור ב:
| Principais autores: | , |
|---|---|
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Iran University of Medical Sciences
2025-05-01
|
| סדרה: | Neurology Letters |
| נושאים: | |
| גישה מקוונת: | https://www.neurologyletters.com/article_220437_bd85211e84319a406a0d5d56fd626a43.pdf |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|