Huntingtin aggregation monitored by dynamic light scattering

An initial stage of fibrillogenesis in solutions of glutathione S-transferase-huntingtin (GST-HD) fusion proteins has been studied by using dynamic light scattering. Two GST-HD systems with poly-l-glutamine (polyGln) extensions of different lengths (20 and 51 residues) have been examined. For both s...

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Detalhes bibliográficos
Main Authors: Georgalis, Yannis, Starikov, E. B., Hollenbach, Birgit, Lurz, Rudi, Scherzinger, Eberhard, Saenger, Wolfram, Lehrach, Hans, Wanker, Erich E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27595/
https://ncbi.nlm.nih.gov/pubmed/9600927
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