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High-affinity single-domain binding proteins with a binary-code interface

High degrees of sequence and conformation complexity found in natural protein interaction interfaces are generally considered essential for achieving tight and specific interactions. However, it has been demonstrated that specific antibodies can be built by using an interface with a binary code cons...

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Detalhes bibliográficos
Main Authors: Koide, Akiko, Gilbreth, Ryan N., Esaki, Kaori, Tereshko, Valentina, Koide, Shohei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871837/
https://ncbi.nlm.nih.gov/pubmed/17420456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700149104
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